Pediatric Emergency Research Canada (PERC): Patient/Family-informed Research Priorities for Pediatric Emergency Medicine.
Liza Bialy, Amy C Plint, Stephen B Freedman, David W Johnson, Janet A Curran, Antonia S Stang
Acad Emerg Med. 2018 Jun
[PMID: 29873867 ]
Treating and reducing anxiety and pain in the paediatric emergency department-TIME FOR ACTION-the TRAPPED quality improvement collaborative.
Evelyne D Trottier, Samina Ali, Jennifer Thull-Freedman, Garth Meckler, Antonia Stang, Robert Porter, Mathieu Blanchet, Alexander Sasha Dubrovsky, April Kam, Raagini Jain, Tania Principi, Gary Joubert, Sylvie Le May, Melissa Chan, Gina Neto, Maryse Lagacé, Jocelyn Gravel
Paediatr Child Health. 2018 Jul; 23(5): e85-e94
[PMID: 30046273 ]
Parental characteristics and perspectives pertaining to neonatal visits to the emergency department: a multicentre survey.
JoAnn Harrold, Mélissa Langevin, Nick Barrowman, Ann E Sprague, Deshayne B Fell, Katherine A Moreau, Thierry Lacaze-Masmonteil, Suzanne Schuh, Gary Joubert, Andrea Moore, Tanya Solano, Roger L Zemek
CMAJ Open. 2018 Sep; 6(3): E423-E429
[PMID: 30266780 ]
Validation and refinement of a clinical decision rule for the use of computed tomography in children with minor head injury in the emergency department.
Martin H Osmond, Terry P Klassen, George A Wells, Jennifer Davidson, Rhonda Correll, Kathy Boutis, Gary Joubert, Serge Gouin, Simi Khangura, Troy Turner, Francois Belanger, Norm Silver, Brett Taylor, Janet Curran, Ian G Stiell
CMAJ. 2018 Jul; 190(27): E816-E822
[PMID: 29986857 ]
Association of Preprocedural Fasting With Outcomes of Emergency Department Sedation in Children.
Maala Bhatt, David W Johnson, Monica Taljaard, Jason Chan, Nick Barrowman, Ken J Farion, Samina Ali, Suzanne Beno, Andrew Dixon, C Michelle McTimoney, Alexander Sasha Dubrovsky, Mark G Roback
JAMA Pediatr. 2018 Jul; 172(7): 678-685
[PMID: 29800944 ]
Pain management practices surrounding lumbar punctures in children: A survey of Canadian emergency physicians.
Naveen Poonai, Victoria Brzozowski, Antonia S Stang, Amy L Drendel, Philippe Boisclair, Michael Miller, Stuart Harman, Samina Ali
CJEM. 2018 May: 1-5
[PMID: 29789038 ]
No association between metoclopramide treatment in ED and reduced risk of post-concussion headache.
Natalie Bresee, Mary Aglipay, Alexander Sasha Dubrovsky, Andrée-Anne Ledoux, Franco Momoli, Jocelyn Gravel, Stephen B Freedman, Karen Barlow, Lawrence Richer, Nicholas J Barrowman, Roger Zemek
Am J Emerg Med. 2018 Apr
[PMID: 29661668 ]
Respiratory Viruses and Treatment Failure in Children With Asthma Exacerbation.
Joanna Merckx, Francine M Ducharme, Christine Martineau, Roger Zemek, Jocelyn Gravel, Dominic Chalut, Naveen Poonai, Caroline Quach
Pediatrics. 2018 Jun; 142(1)
[PMID: 29866794 ]
Relationship between enteric pathogens and acute gastroenteritis disease severity: a prospective cohort study.
J Xie, A Nettel-Aguirre, B E Lee, L Chui, X L Pang, R Zhuo, B Parsons, O G Vanderkooi, P I Tarr, S Ali, J A Dickinson, E Hagen, L W Svenson, S E MacDonald, S J Drews, R Tellier, T Graham, M Lavoie, J MacDonald, S B Freedman
Clin Microbiol Infect. 2018 Jun
[PMID: 29964235 ]
Preferred learning modalities and practice for critical skills: a global survey of paediatric emergency medicine clinicians.
Simon S Craig, Marc Auerbach, John Alexander Cheek, Franz E Babl, Ed Oakley, Lucia Nguyen, Arjun Rao, Sarah Dalton, Mark D Lyttle, Santiago Mintegi, Joshua Nagler, Rakesh D Mistry, Andrew Dixon, Pedro Rino, Guillermo Kohn-Loncarica, Stuart R Dalziel, Nathan Kuppermann, David Johnson, Martin Osmond, Jim Chamberlain, Charles Macias, Anupam Kharbanda, Patrick van de Voord, Ronan O’Sullivan
Emerg Med J. 2018 Oct
[PMID: 30327413 ]
Natural Progression of Symptom Change and Recovery From Concussion in a Pediatric Population.
Andrée-Anne Ledoux, Ken Tang, Keith O Yeates, Martin V Pusic, Kathy Boutis, William R Craig, Jocelyn Gravel, Stephen B Freedman, Isabelle Gagnon, Gerard A Gioia, Martin H Osmond, Roger L Zemek
JAMA Pediatr. 2018 Nov: e183820
[PMID: 30398522 ]
Multicenter Trial of a Combination Probiotic for Children with Gastroenteritis.
Stephen B Freedman, Sarah Williamson-Urquhart, Ken J Farion, Serge Gouin, Andrew R Willan, Naveen Poonai, Katrina Hurley, Philip M Sherman, Yaron Finkelstein, Bonita E Lee, Xiao-Li Pang, Linda Chui, David Schnadower, Jianling Xie, Marc Gorelick, Suzanne Schuh
N Engl J Med. 2018 Nov; 379(21): 2015-2026
[PMID: 30462939 ]
Prehospital dexamethasone administration in children with croup: a medical record review.
Samina Ali, Aaron Moodley, Amrita Bhattacharjee, Eddie Chang, Allison Kabaroff, Kevin Lobay, Dominic Allain
Open Access Emerg Med. 2018 Nov; 10: 141-147
[PMID: 30410413 ]
Association between ondansetron use and symptom persistence in children with concussions: A 5P substudy.
Jocelyn Gravel, Kathy Boutis, Ken Tang, Miriam H Beauchamp, Stephen B Freedman, Alexander Sasha Dubrovsky, Isabelle Gagnon, Frank Momoli, Roger Zemek
CJEM. 2018 Jun; 21(2): 204-210
[PMID: 29877168 ]
Performance of Stool Testing Recommendations for Acute Gastroenteritis when Used to Identify Children with Nine Potential Bacterial Enteropathogens.
Gillian A M Tarr, Linda Chui, Bonita E Lee, Xiao-Li Pang, Samina Ali, Alberto Nettel-Aguirre, Otto G Vanderkooi, Byron M Berenger, James Dickinson, Phillip I Tarr, Steven Drews, Judy MacDonald, Kelly Kim, Stephen B Freedman
Clin Infect Dis. 2018 Dec
[PMID: 30517612 ]
November 2018
Congratulations to the Past PERC Chair, Dr. Stephen Freedman, et al. who have had their study “Multicenter Trial of a Combination Probiotic for Children with Gastroenteritis” published in the prestigious New England Journal of Medicine today. Citation and link to the journal article below:
Stephen B Freedman MDCM, Sarah Williamson-Urquhart B.Sc.Kin, Ken J Farion MD, Serge Gouin MDCM, Andrew R Willan Ph.D, Naveen Poonai MD, Katrina Hurley MD, Philip M Sherman MD, Yaron Finkelstein MD, Bonita E Lee MD, Xiao-Li Pang Ph.d, Linda Chui Ph.d, David Schnadower MD MPH, Jianling Xie MD MPH, Mark Gorelick MD and Suzanne Schuh MD for the PERC PROGUT Trial Group.
https://www.nejm.org/doi/pdf/10.1056/NEJMoa1802597
The six PERC sites that were involved in the study were Alberta Children’s Hospital, Sick Kids, London, IWK, CHEO and Ste. Justine.
See below for the media coverage links.
Canadian Media Coverage:
- https://globalnews.ca/news/4686693/calgary-study-probiotics-kids-intestinal-infections/
- https://www.cbc.ca/news/canada/calgary/probiotics-study-research-calgary-medicine-new-england-journal-freedman-children-1.4914601
- https://calgary.ctvnews.ca/study-led-by-u-of-c-researcher-refutes-claim-probiotics-assist-children-suffering-from-gastroenteritis-1.4186925
- https://www.btcalgary.ca/videos/probiotics-and-children/
- https://www.theglobeandmail.com/life/article-two-studies-find-probiotic-therapy-ineffective-against-intestinal/?cmpid=rss
International Media Coverage:
Malaysia
- https://www.freemalaysiatoday.com/category/leisure/2018/11/22/probiotics-no-help-to-kids-with-stomach-flu-say-studies/
- https://www.nst.com.my/world/2018/11/433396/probiotics-no-help-kids-stomach-flu-studies
India:
USA:
- https://technology.inquirer.net/81450/probiotics-are-no-help-to-kids-with-stomach-flu-studies
- https://www.npr.org/sections/health-shots/2018/11/21/669373363/probiotics-found-to-be-ineffective-for-easing-symptoms-of-kids-stomach-bugs
PERC Site Coverage
Great work everyone on this ground breaking study on probiotics for children with gastroenteritis!
Be sure to follow the PERC network here on Twitter for the latest updates and further knowledge translation on PERC studies – twitter handle: @PERC_Network. If you have any successes, relevant information or other PERC publications you would like shared on social media, feel free to send them to the PERC Coordinator, Becky Emerton (rebecca.emerton@ahs.ca), we would be happy to tweet about them with our ever-growing following.