Completed Projects

Title: A Randomized Clinical Trial of Oral Analgesics Utilization for Childhood Musculoskeletal Injuries (OUCH Trial)

Principal Investigator: Sylvie Lemay
Study Design: RCT
Funding Agency: CIHR
Funding Amount: $584,860
Project Summary & Impact: Musculoskeletal injuries (MSK-I) in children are very common and almost universally painful. Pain management of MSK-I in the Emergency Department (ED) varies greatly between Canadian hospitals and, overall, pain is poorly treated. This sub-optimal pain treatment can have significant acute and chronic negative effects. Previous studies have determined that monotherapy with ibuprofen, one of the most commonly prescribed oral analgesics in the ED, is likely providing inadequate pain management for children. To date, few studies have focused on the efficacy of a combination of an anti-inflammatory drug (eg ibuprofen) and an oral opioid (eg morphine). Such a combination of analgesics is known to potentiate pain relief by blocking pain at the level of both the peripheral and central nervous system. To our knowledge, no previous studies have looked at the efficacy and safety of this combination of medications in the pediatric ED.

Primary aims and objectives:   To assess the efficacy of a combination of oral morphine and ibuprofen for acute pain management in children with MSK-I in the ED.

Primary outcomes Pain intensity score < 30 mm on the VAS at 60-minutes after treatment administration (T-60)

Secondary outcomes Oxygen saturation, level of sedation/alertness, and vital signs were monitored at set time points in the study.

Title: Predictors of Severe H1N1 Infection in Children Presenting within Pediatric Emergency Research Networks (PERN): Retrospective Case-Control Study

Principal Investigator: Stuart Dalziel
Study Design: Retrospective Case-Control
Funding Agency: None
Funding Amount: None
Project Summary & Impact:

Title: Determinants of Oral Corticosteroid Responsiveness in Wheezing Asthmatic Youth (DOORWAY)

Principal Investigator: Francine Ducharme
Study Design: Prospective Cohort
Funding Agency: CIHR
Funding Amount: $1,899,256
Project Summary & Impact:

Title: Pilot Study of a Computer-based Brief Intervention for Adolescent Alcohol Misuse in the Emergency Department

Principal Investigator: Mandi Newton
Study Design: RCT
Funding Agency: Norlien Foundation and WCHRI
Funding Amount: $59,000
Project Summary & Impact:

Title: Canadian Bronchiolitis Epinephrine/Steroid Trial (CanBEST)

Principal Investigator: Amy Plint
Study Design: RCT
Funding Agency: CIHR
Funding Amount: $1,951,932
Project Summary & Impact:

Title: Efficacy of Nebulized Magnesium in Children with Acute Asthma

Principal Investigator: Suzanne Schuh
Study Design: RCT
Funding Agency: Thrasher Foundation
Funding Amount: $500,920
Project Summary & Impact:

Title: Using Genomics to Address Drug Safety in Children with Traumatic Injury: An Innovative Approach to a Common Problem

Principal Investigator: Samina Ali
Study Design: Prospective Cohort
Funding Agency: CIHR Catlyst Grant
Funding Amount: $99,848
Project Summary & Impact:

Title: Ascertainment of Abuse Related Fractures in Two Pediatric Emergency Departments

Principal Investigator: Kathy Boutis
Study Design: Retrospective Cohort
Funding Agency: Child Health Injury reporting and Prevention Program
Funding Amount: $8,014
Project Summary & Impact:

Title: Controlled Radiography for Ankle Injury Cases in Kids in the Emergency Department (CRACKED) Study: Implementation of Best Evidence for Imaging of Paediatric Ankle Injuries

Principal Investigator: Kathy Boutis
Study Design: Interrupted time series with pair-matched control design
Funding Agency: CIHR and Physician Services Incorporated
Funding Amount: $270,000
Project Summary & Impact:

Title: Salter-Harris I Fracture of Distal Fibula: Clinical Suspicion versus Reality

Principal Investigator: Kathy Boutis
Study Design: Prospective Cohort
Funding Agency: Physician Services Incorporated
Funding Amount: $170,000
Project Summary & Impact:

Title: Validation of Ottawa Knee Rule

Principal Investigator: Blake Bulloch
Study Design: Prospective Cohort
Funding Agency: 
Funding Amount: 
Project Summary & Impact:

Title: Emergency mental health services for children and youth: Results of a multi-site study

Principal Investigator: Mario Cappelli
Study Design: Prospective Cohort
Funding Agency: None
Funding Amount: NA
Project Summary & Impact:

Title: Impact of Emergency Department Probiotic Treatment of Pediatric Gastroenteritis on Daycare Attendance: RCT and Economic Analysis

Principal Investigator: Stephen Freedman
Study Design: RCT
Funding Agency: Institut Rosell Inc.
Funding Amount: $155,000
Project Summary & Impact:

Title: A Prospective Assessment of Practice Variation in the Treatment of Pediatric Gastroenteritis

Principal Investigator: Stephen Freedman
Study Design: Prospective Cohort
Funding Agency: None
Funding Amount: NA
Project Summary & Impact:

Title: Practice variations in the treatment of febrile infants among pediatric emergency physicians

Principal Investigator: Ran Goldman
Study Design: Prospective Cohort
Funding Agency: None
Funding Amount: NA
Project Summary & Impact:

Title: Validity of the Canadian Triage and Acuity Scale for Children: A multi-centre database study

Principal Investigator: Jocelyn Gravel
Study Design: Prospective Cohort
Funding Agency: CIHR and Physician Services Incorporated
Funding Amount: $128,500
Project Summary & Impact:

Title: Performance of the Canadian Triage and Acuity Scale for Children: A Multicenter Database Study

Principal Investigator: Jocelyn Gravel
Study Design: Retrospective Cohort
Funding Agency: None
Funding Amount: NA
Project Summary & Impact:

Title: Derivation of a Clinical Decision Rule for Skull Radiography of Young Children with Minor Head Trauma

Principal Investigator: Jocelyn Gravel
Study Design: Prospective Cohort
Funding Agency: FRSQ
Funding Amount: $150,000
Project Summary & Impact:

Title: Storytelling as a Communication Tool Aimed at Parents and Children Presenting to the Emergency Department with Common Disease Conditions

Principal Investigator: Lisa Hartling
Study Design: RCT
Funding Agency: CIHR Team Grant
Funding Amount: $219,503
Project Summary & Impact:

Title: A Cluster Controlled Trial Comparing Three Methods of Disseminating Practice Guidelines for Children with Croup

Principal Investigator: David Johnson
Study Design: RCT
Funding Agency: CIHR
Funding Amount: $811,304
Project Summary & Impact:

Title: The Implementation of a Clinical Practice Guideline for Managing Croup at Calgary Health Region Emergency Departments and Urgent Care Clinics

Principal Investigator: David Johnson
Study Design: Prospective Cohort
Funding Agency: Calgary Health Region: Knowledge Translation Seed Grant Competition and Child and Women's Health Portfolio
Funding Amount: $75,000
Project Summary & Impact:

Title: A randomized trial of single dose of oral dexamethasone for mild croup

Principal Investigator: David Johnson
Study Design: RCT
Funding Agency: CIHR; Alberta Children's Hospital Foundation; CHEO RI; Stollery Children's Hospital Foundation
Funding Amount: 
Project Summary & Impact:

Title: Use Of Lorazepam For The Treatment Of Pediatric Status Epilepticus: A Randomized, Double-Blinded Trial Of Lorazepam And Diazepam

Principal Investigator: David Johnson
Study Design: RCT
Funding Agency: None
Funding Amount: NA
Project Summary & Impact:

Title: Viral Etiologies of Bronchiolitis in a Large Outpatient Cohort

Principal Investigator: Tim Karnauchow
Study Design: Retrospective Cohort
Funding Agency: Ontario Thoracic Society, Ontario Lung Association, CHEO Research Institute
Funding Amount: $90,000
Project Summary & Impact:

Title: Improving outcomes for ill and injured children in emergency departments

Principal Investigator: Terry Klassen
Study Design: Infrastructure (PERC sites, PERC coordinator, Knowledge Broker)
Funding Agency: CIHR Team Grant
Funding Amount: $1,963,740
Project Summary & Impact:

Title: Caring for Children and Youth with Emergency Mental Health Needs

Principal Investigator: Mandi Newton
Study Design: Cross-sectional survey
Funding Agency: CIHR
Funding Amount: $94,655
Project Summary & Impact:

Title: A study to derive a clinical decision rule for the use of computed tomography in children with minor head injury

Principal Investigator: Martin Osmond
Study Design: Prospective Cohort
Funding Agency: CIHR
Funding Amount: $632,694
Project Summary & Impact:

Title: A study to validate a clinical decision rule for the use of computed tomography in children with minor head injury

Principal Investigator: Martin Osmond
Study Design: Prospective Cohort
Funding Agency: CIHR
Funding Amount: $632,694
Project Summary & Impact:

Title: Evaluation of an Active Strategy to Implement the Canadian Pediatric CT Head Rule: Phase III

Principal Investigator: Martin Osmond
Study Design: Pathway Implementation
Funding Agency: CIHR Team Grant
Funding Amount: $391,138
Project Summary & Impact:

Title: PERC Spacer Study

Principal Investigator: Martin Osmond
Study Design: Cross Sectional Mailed Survey
Funding Agency: None
Funding Amount: NA
Project Summary & Impact:

Title: A Study to Derive a Clinical Decision Rule for Predicting Severe Bronchiolitis

Principal Investigator: Amy Plint
Study Design: Prospective Cohort
Funding Agency: Ontario Lung Association
Funding Amount: $87,764
Project Summary & Impact:

Title: Bronchiolitis Practice Variation Study

Principal Investigator: Amy Plint
Study Design: Prospective Cohort
Funding Agency: 
Funding Amount: 
Project Summary & Impact:

Title: Management and Outcomes of Children Presenting with Bronchiolitis to Ontario Community Emergency Departments

Principal Investigator: Amy Plint
Study Design: Retrospective Cohort
Funding Agency: CIHR Team Grant
Funding Amount: $365,403
Project Summary & Impact:

Title: Validation of the Ottawa Ankle Rule

Principal Investigator: Amy Plint
Study Design: Prospective Cohort
Funding Agency: CHEO Research Institute
Funding Amount: 
Project Summary & Impact:

Title: Developing Measures of Quality for the Emergency Department Management of Pediatric Suicide-Related Behaviors

Principal Investigator: Anne Rhodes
Study Design: Cross-sectional survey
Funding Agency: Child Welfare League of Canada; the Ontario Association for Children's Aid Societies; the Ontario Centre of Excellence for Child and Youth Mental Health; the Injury and Child Maltreatment Section, Health Surveillance and Epidemiology Division, Public Health Agency of Canada
Funding Amount: $265,000
Project Summary & Impact:

Title: Efficacy of combination therapy with intravenous ketorolac and metoclopramide for pediatric migraine therapy in the Emergency Department - a randomized placebo controlled trial

Principal Investigator: Lawrence Richer
Study Design: RCT
Funding Agency: CIHR Catlyst Grant
Funding Amount: $99,961
Project Summary & Impact:

Title: Emergency Department Management of Acute Migraine in Children: National Multi-site Practice Variation Study

Principal Investigator: Lawrence Richer
Study Design: Retrospective Cohort
Funding Agency: Stollery Children's Foundation
Funding Amount: $29,500
Project Summary & Impact:

Title: Practice patterns in asthma discharge pharmacotherapy in pediatric emergency departments

Principal Investigator: Suzanne Schuh
Study Design: Retrospective Cohort
Funding Agency: 
Funding Amount: 
Project Summary & Impact:

Title: A Qualitative Study of Barriers and Supports to Implementation of MDI/Spacer Use in Canadian Emergency Departments

Principal Investigator: Shannon Scott
Study Design: Comparative case study design
Funding Agency: CIHR Team Grant
Funding Amount: $182,846
Project Summary & Impact:

Title: Understanding Storytelling as a Knowledge Transfer Technique for Parents

Principal Investigator: Shannon Scott
Study Design: Qualitative design about Knowledge Transfer
Funding Agency: None
Funding Amount: NA
Project Summary & Impact:

Title: The Development of Quality Indicators for High Acuity Pediatric Conditions Requiring Emergency Department Care

Principal Investigator: Antonia Stang
Study Design: systematic, multiphase, Rand-modified Delphi method congruent with the process for quality indicator development
Funding Agency: CIHR
Funding Amount: $81,254
Project Summary & Impact:

Title: Pediatric Pain Management in the Emergency Department: The Triage Nurses' Perspective

Principal Investigator: Daina Thomas
Study Design: Descriptive cross-sectional survey
Funding Agency: None
Funding Amount: NA
Project Summary & Impact:

Title: Variations in the Diagnosis and Management of Appendicitis at Canadian Pediatric Emergency Departments

Principal Investigator: Graham Thompson
Study Design: Retrospective Cohort
Funding Agency: University of Calgary
Funding Amount: $15,624
Project Summary & Impact:

Title: Predicting Persistent Postconcussive Problems in Pediatrics (5P)

Principal Investigator: Roger Zemek
Study Design: Prospective Cohort
Funding Agency: CIHR Team Grant
Funding Amount: $1,273,705
Project Summary & Impact: